Clinical Trial - Activ Daily

Not Just Backed by Science—Proven by It.

Others talk science—we invested in it. Activ Daily is backed by a two-year clinical trial, proving what no one else dares to test.

Shop Now
Proven by science, not just backed by it.
Not just claims. Clinical proof.
Tested. Proven. Trusted.
Proven by science, not just backed by it.
Not just claims. Clinical proof.
Tested. Proven. Trusted.
Proven by science, not just backed by it.
Not just claims. Clinical proof.
Tested. Proven. Trusted.
Activ Daily

Our goal is simple: to fix every dog with gut issues in Australia—and stop those issues from coming back.

At Activ Dog Health, we believe real results demand real science. Unfortunately, the pet supplement market remains relatively unregulated—allowing companies to make wild claims without evidence. That’s exactly why we set our own standards. We manufacture to human-grade quality and prove our science through rigorous clinical trials. No one else in this industry goes to the lengths we do—and that’s what sets us apart.

We did what no one else was willing to do. We invested years into research and development and partnered with the University of Adelaide to conduct a full clinical trial—not just on individual ingredients, but on our entire formula. While other companies scramble to ride the wave we created—throwing around laughable claims that “some” of their ingredients were tested—we’ve already done the hard work. Testing a single strain in isolation is meaningless when the full product hasn’t been proven to work.

We didn’t take shortcuts. We didn’t throw together a cheap probiotic meal topper that risks contamination and delivers minimal benefit. We created a stable, air-dried treat containing species-specific Prebiotics, Probiotics, and Postbiotics—delivering results you can see.

More than that, we developed and own our own trademarked sub-strains—specifically for dogs. Backed by our exclusive Microbiome Assist™ technology, these strains were created through rigorous selection and refinement to deliver targeted health benefits. This isn’t a rebranded human probiotic. It’s purpose-built innovation—clinically proven through a two-year, university-led trial. Published. Peer-reviewed. Unmatched.

While others make noise with marketing, we lead with evidence. Activ Daily isn’t just another supplement. It’s the benchmark.

Clinical Benefits of Activ Daily

Activ Daily targets the root cause of multiple canine health issues by restoring balance to the gut microbiome through a Prebiotic, Probiotic & Postbiotic approach. Backed by a two-year University of Adelaide clinical trial and published in Veterinary Dermatology (2025), Activ Daily provides systemic benefits via the gut-skin and gut-immune axes.

Key Clinical Outcomes:

  • Dermatological Health – Significant reduction in Staphylococcus pseudintermedius colonisation (p=0.02) and improvement in skin barrier function; effective for dogs with recurrent pyoderma, hot spots, and chronic dermatitis.
  • Allergy & Atopy Management – Reduction in pruritus and secondary skin infections by modulating immune response and restoring microbial diversity.
  • Gastrointestinal Function – Improved stool consistency, reduced diarrhoea incidence, and enhanced nutrient absorption.
  • Immune Support – Strengthened mucosal immunity via increased populations of Lactobacillus acidophilus (7x), Roseomonas vastitus (40x), and Dubosiella newyorkensis (37x).
  • Yeast & Dysbiosis Control – Corrects overgrowth of pathogenic bacteria and yeast by competitive inhibition and improved colonisation resistance.
  • Neurobehavioural Support – Postbiotics and psychobiotic activity contribute to reduced anxiety-related behaviours and improved stress resilience.
  • Post-Antibiotic Recovery – Restores gut microbial diversity following antibiotic-induced dysbiosis, accelerating recovery and preventing secondary infections.
  • Oral & Dental HealthAscophyllum nodosum (seaweed) reduces plaque, tartar formation, and halitosis by altering oral biofilm.

Activ Daily is expertly formulated to enhance your dog’s digestive process, ensuring they get the most out of every meal. No matter how nutritious your dog's diet may be, without a balanced microbiome, true health remains out of reach. Activ Daily addresses this gap, promoting optimal gut health.

By stabilizing the gut environment, Activ Daily helps reduce the occurrence of diarrhea, making each day more comfortable and carefree for your dog.

Say goodbye to uncomfortable rashes and itchy skin. Our formula supports a healthy immune system, leading to clearer, healthier skin.

A balanced gut is crucial for overall well-being, including mental health. Activ Daily aids in managing anxiety, promoting a calmer, more relaxed demeanour.

Enhanced with immune-boosting properties, Activ Daily helps your dog resist and recover from infections more effectively.

Antibiotics can disrupt your dog's natural gut flora. Our postbiotics help restore balance, ensuring a smooth recovery and robust health.

By maintaining a healthy microbial balance, Activ Daily significantly reduces the risk of yeast infections, keeping your dog comfortable and itch-free.

No more incessant paw licking or scratching. With improved overall health, these behaviours often linked to discomfort or allergies become a thing of the past.

Make the smart choice for your dog's long-term health and well-being. Choose Activ Daily – because they deserve more than just good nutrition; they deserve a foundation for a lifetime of health.

Shop Now

We’re on a Mission to Fix Every Dog in Australia

At Activ Dog Health, our goal is to fix every dog in Australia with gut issues—and stop those problems from coming back. Activ Daily isn’t a quick fix. It’s a proven, long-term solution that restores and protects gut health, so your dog can thrive for life.

The Power of Prevention

Activ Daily isn’t just for fixing problems—it’s for stopping them before they begin. With our powerful triple-action formula of Prebiotics, Probiotics, and Postbiotics, you’re not just supporting your dog’s health today—you’re protecting it for the long term. It’s not just about treating symptoms; it’s about building resilience from the inside out.

Prevent the problems before they even start.

10 reasons for using "Activ Daily" Postbiotic

Discover the top 10 reasons why "Activ Daily" Postbiotic is a must for your dog’s health and well-being. From enhancing digestion to boosting immunity, "Activ Daily" offers a revolutionary approach to maintaining a balanced gut microbiome, tackling issues from the inside out. Designed for everyday use, our Triple Action Postbiotic is scientifically formulated to address the root causes of common health concerns, promoting overall vitality and a happier, healthier life for your dog.

Dog Postbiotics can help alleviate digestive issues due to stress or illness

When your pet is sick or feeling stressed (for example, when she’s boarded at a kennel or is moved to a new home), the balance between healthy and illness-causing microbes in her gut can become disrupted. This can lead to issues like diarrhea, gas, cramping, and bad breath. Probiotics have been shown to reduce the duration of diarrhea in dogs from seven to four days.

Dog Probiotics decrease the side effects of antibiotics

Antibiotics do not discriminate between good and bad bacteria. And while antibiotics are effective at fighting infection, they may also cause diarrhoea or other gastrointestinal side effects in your dog. If you know ahead of time that your loyal companion will be taking antibiotics, you may be able to ward off unpleasant side effects by starting your dog on probiotics a few days in advance and continuing them beyond the duration of antibiotic treatment.

Pets with chronic gastrointestinal distress will thank you

If you have a pet that suffers from chronic intestinal distress, try giving her a high-quality dog probiotic with prebiotics daily to help replenish her gut with healthy bacteria. This practice can support a healthy inflammatory response in her GI tract and ultimately help her feel better.

Healthy gut bacteria may positively impact behaviour

One of the first signs your pet isn’t feeling well is a behavioural change. As humans do, dogs with unhealthy gut bacteria and digestion problems may also experience emotional issues. These might include behaviours like excessive licking or other obsessive-compulsive actions. So, in the process of supporting digestive health, probiotics might also improve your dog’s behaviour.

Senior dogs need extra TLC to keep them healthy and feeling good

Older dogs are much more susceptible to weakened immune systems. And since almost 70 percent of immune cells are in the gut, promoting the growth of healthy, or ‘good,’ bacteria in the GI tract is a sound way to help boost immunity. Your dog’s gut flora is very important to her overall health and well-being and may be the key to living a long, happy life.

Dog probiotics can help prevent issues related to unhealthy bacterial balance

Constipation is no fun, for humans and dogs alike. Painful gas, bloating and cramping can, if left untreated, also lead to vomiting, lethargy, and loss of appetite. Together, exercise, fresh water, and dog probiotics support a healthy gut environment, so that your pet doesn’t have to suffer from painful issues related to unhealthy gut bacteria.

Dog probiotics can help minimize tummy upset due to a change in food

If your dog has been eating the same food for a long time and you make a switch, I can almost guarantee your furry friend will experience gastrointestinal distress as a result. Prep your dog’s gut with probiotics to level the playing field against the ‘good’ and ‘bad’ bacteria before changing to a different food.

Dog probiotics can help reduce skin allergy symptoms

Allergies (which are essentially misguided immune system responses) are on the rise in humans and dogs alike. Researchers have attributed this, in part, to an imbalance of bacteria in the gut. Because gut and immune health are so intertwined, giving your dog probiotics may lessen skin allergy symptoms. Several studies support this theory, having demonstrated that dog probiotics may be effective for allergy management.

Who doesn’t want healthier teeth?

Preliminary research suggests that giving your dog probiotics could also support her dental health. That’s reason for both of you to smile!

A healthier gut can mean better skin, coat, and breath

Promoting the growth of healthy gut bacteria can have all sorts of beneficial effects on the body, making you look and feel better. When you give your pup a daily dog probiotic you’ll likely see the benefits on the outside of her body, as she begins to feel better on the inside. 

Clinically Proven to Support Skin Health and Microbiome Balance in Dogs

A groundbreaking peer-reviewed study published in Veterinary Dermatology (2025) has confirmed that daily oral supplementation with Activ Daily significantly improves the skin microbiota in dogs. This landmark study, led by researchers from the University of Adelaide, is the first of its kind to examine the effects of a combined Prebiotic, Probiotic and Postbiotic supplement on the canine skin microbiome using advanced full-length 16S rRNA gene sequencing—widely regarded as the gold standard in microbiome analysis.

The study followed twelve Golden Retrievers over a 90-day period, all living in the same controlled environment to eliminate external variables. Throughout the study, the dogs received a daily 10g Activ Daily chew, formulated with four proprietary strains of beneficial bacteria—Lactobacillus acidophilus, Lactobacillus rhamnosus, Enterococcus faecium, and Bifidobacterium animalis—developed specifically for dogs. Swab samples were collected before supplementation, and again at Day 30 and Day 90, from both the axillae (underarm area) and inguinal (groin) regions.

Results were remarkable. After 90 days of supplementation, researchers observed a sevenfold increase in Lactobacillus acidophilus, a known skin-beneficial species included in the Activ Daily formula. Two other health-promoting bacteria also saw dramatic increases: Dubosiella newyorkensis increased 37-fold, and Roseomonas vastitus increased 40-fold. These bacterial strains are linked to improved immune regulation, stronger skin barrier function, and reduced inflammation—key factors in preventing chronic skin conditions.

Importantly, culture-based methods showed a statistically significant reduction in Staphylococcus pseudintermedius, a pathogen commonly associated with canine skin infections and atopic dermatitis. While this harmful species remained present in low levels overall, its prevalence was notably reduced in the group receiving Activ Daily. Sequencing data also revealed a broad reduction in Staphylococcus species over time, confirming that Activ Daily helped shift the microbiome toward a healthier and more balanced state.

This study provides the first high-resolution, species-level insight into how an oral dog supplement can positively influence skin health through the gut-skin axis. Previous studies had only examined topical or short-read sequencing methods, which lacked the precision and reliability achieved here. Thanks to the use of PacBio HiFi sequencing technology, the research team was able to identify over 3,800 bacterial species and track significant changes with confidence.

The study's findings support what dog owners using Activ Daily have already experienced—visible improvements in coat condition, skin health, and overall well-being. Whether your dog struggles with skin irritations or you're simply looking to maintain optimal health, Activ Daily delivers scientifically validated results from the inside out. And unlike many generic supplements using human probiotic strains, Activ Daily was developed with species-specific strains tailored exclusively for dogs, ensuring maximum safety and effectiveness.

This extensive clinical validation reinforces Activ Daily’s status as the most advanced canine probiotic and postbiotic supplement available today. By restoring microbial diversity, reducing pathogenic bacteria, and enhancing the presence of beneficial species, Activ Daily offers a natural, antibiotic-free way to support your dog’s skin health, immunity, and overall vitality.